PhD Student, Coventry, UK
I am a PhD student in the Dowson group at the University of Warwick. My research centres on peptidoglycan, a structural molecule in the cell walls of bacteria that is one of the main targets of antibiotics. β-lactam antibiotics inhibit the enzymes that build this cross-linked structure of peptidoglycan, thereby causing cell death.
The focus of my project is the mechanism by which resistance to β-lactam antibiotics develops in Streptococcus pneumoniae. Development of resistance in S. pneumoniae requires both alteration of some of the enzymes that build peptidoglycan, and also the production of certain precursors for peptidoglycan synthesis.