Staff Research Scientist, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
I am a peptide designer who has a great liking for designing antibiotic peptides. I am alarmed but not unduly alarmed about antibiotic resistance since I know that antibiotics and resistance to antibiotics may be the language in which microbes talk to each other. There is need to fathom this reality and to think creatively to tackle the challenge of clinical antibiotic resistance. My laboratory has unearthed several principles which go into the making of potent, selective and broad spectrum antibiotic peptides against antibiotic resistant strains like the MRSA. We have also discovered the ability of antibiotic peptides to show strong synergy with conventional antibiotics. My other major interest is discovery and design of novel drugs against malaria.