Lecturer in Biochemistry, Swansea University Institute of Life Science, UK
My research group specialises in the microbiology and (eco)physiology of soil bacteria, especially streptomycetes and other actinomycetes, the producers of the majority of antibiotics used in medicine. We have pioneered bimolecular extraction and characterisation of the molecular and ecosystem level, which includes studies of cryptic or elusive natural product biosynthesis under environmental conditions. In addition, we use functional genomics approaches for rational design and metabolic engineering of strains to improve antibiotic production.
I am also keen to inform others, including researchers, clinicians, policy makers, politicians and the public, on sustainable use of antibiotics, the dangers of increased resistance to antibiotics, and the urgent need for next-generation antibiotics.