Santosh Kumar Tiwari

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Assistant Professor, Maharshi Dayanand University, Rohtak, India

My group is working on purification and characterization of antimicrobial peptides (AMPs) of lactic acid bacteria and haloarchaea. These peptides are being characterized for the application
as food bio-preservative and in therapeutics as an alternative to clinical antibiotics. The antimicrobial peptides from lactic acid bacteria are mostly non-toxic and safe for human
consumption as secreted by GRAS status organism. The mandate of the laboratory is to find out the alternative to clinical antibiotics against which number of pathogens become resistance.
Development of resistance against peptide antibiotics is either difficult or not possible. We have isolated various bacteriocin producing lactic acid bacteria from soil and food samples. The
presence of peptides has been detected in culture supernatant. These are being characterized for their applications. Characterization of AMPs from haloarchaea isolated from salt lake is the
other objective of the laboratory.

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