Antibiotic development through the years.
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It is worth noting that the antibiotic pipeline for infections by organisms that are causing current clinical concerns (i.e. problematic Gram negative pathogens) essentially dried up in the mid-1960s.
So much examined, so much written & still so few new agents.
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Please see link below to Professor Laura Piddock’s letter published in New Scientist on 26th March 2013. Laura applauds Dame Sally Davies’ activities and awareness-raising of the antibiotic crisis and highlights herself the need for new discovery, research and development of antibiotics. http://www.newscientist.com/article/mg21729100.900-antibiotic-crisis.html
Professor Laura Piddock, Director of Antibiotic Action was invited to give comment and interviews on the need for the discovery and development of new antibiotics following release of the CMO’s Annual Report (Vol 2) on 11 March 2013. Below is a selection of press coverage, both direct and syndicated, each offering helpful overviews of the [...]
Chief Medical Officer Annual Report: Volume Two: Infections and the rise of antimicrobial resistance
On 11th March 2013, the CMO, Professor Dame Sally Davies published her Annual Report (Vol 2) Infections and the rise of antimicrobial resistance. The report takes and indepth look at antimicrobial resistance, described as a great a global threat as terrorism. The report, which makes 17 recommendations to named organisations on how to address the [...]
Explainer: what are antibiotics? By Matthew Cooper, University of Queensland and Mark Blaskovich, University of Queensland You’ve got a high fever, severe cough and find it hard to breathe – all symptoms of severe pneumonia. Before antibiotics, you’d likely be dead within ten days. In fact, before we had these amazing drugs, infections caused by [...]
Cavalier use of medicines presents drug companies with a daunting task: Andrew Jack, Financial Times